By Andre; Renfroe, Burt; Watthey, Jeffrey W. H. Rosowsky
Dibenzodiazepines and different Tricyclic Diazepine platforms (J. Watthey & J. Stanton).
Monocyclic and Condensed Triazepines and Tetrazepine (N. Peet).Content:
Chapter I Dibenzodiazepines and different Tricyclic Diazepine structures (pages 1–717): Jeffrey W. H. Watthey and James L. Stanton
Chapter II Monocyclic and Condensed Triazepines and Tetrazepines (pages 719–842): Norton P. Peet
Read Online or Download Chemistry of Heterocyclic Compounds: Azepines, Part 2, Volume 43 PDF
Best chemistry books
Prior to now fifteen years there was a dramatic bring up within the variety of varied surfaces whose buildings were decided experimentally. for instance, while in 1979 there have been in basic terms 25 recorded adsorption buildings, up to now there are greater than 250. This quantity is accordingly a well timed overview of the state of the art during this dynamic box.
This e-book is pretty well to the purpose, with out placing every little thing into riddles and beating round the bush to confuse you.
- Heterogeneous Catalysis and Fine Chemicals II: Proceedings of the 2nd International Symposium, Poitiers, October 2-5, 1990
- Aspects of African Biodiversity: Proceedings of the Pan Africa Chemistry Network Biodiversity Conference Nairobi, 10-12 September 2008 (Special Publications)
- Unimolecular and Supramolecular Electronics I: Chemistry and Physics Meet at Metal-Molecule Interfaces
- Monohydric Alcohols. Manufacture, Applications, and Chemistry
- Historic Textile and Paper Materials. Conservation and Characterization
- Thermochemistry and Kinetics for the Oxidative Degradation of Dibenzofuran and Precursors
Additional resources for Chemistry of Heterocyclic Compounds: Azepines, Part 2, Volume 43
The synthesis of 43 (Y = NMe,) can also be achieved directly from 42 under Eschweiler-Clarke conditions (30). V. TABLE 4. 5,5,7-Systems 15 TETRAZALO[ 1 ,5-a]THIEN0[3,2-fl[1,4]DIAZEPINES Structure R! R2 X Yield (%) mp C'C) Refs. 42 42 42 43 (Y 43 (Y H H Me H Et Me Me Et CI CI CI CI 80 135- 136 122-123 149- 150 170- 17 I" 29 29 29 30 Me Me CI 189- 190 30 = NMeZ) = NMe,) 77 77 "Oxalate. 2. [1,2,4]0xadiazolo[4,3-a]thieno[3,2-Jl[l,4]diazepines [ 1,2,4]0xadiazolo[4,3-~]thieno[3,2--[ 1,4]diazepines were prepared as shown in Eq.
TABLE 14. IMIDAZO[I ,2-a]THIEN0[3,2-f][ I ,4]DIAZEPINES ~~ R, R2 X H H 0-CI H H H H H H H H H Me Et H Me Et Et Et Et Et Et Me H H “Refs. 29 and 30. 0-c1 0-CI o-Br 0-F P-F o-Me0 p-Me0 0-CI Yield (%) 80 78 mp Salt 124- I27 243-245 96-98 156- I57 252-253 180-1 82 237-238 95-96 116-1 17 215-216 173-175 131-132 HCI ~~ 2HCI $ N 0x1 Et Et Et H H H “Refs. 30 and 36. N 0-CI Et H 0-c1 0-CI 0-c1 0-c1 0-c1 n WNMe f-7 73 NEl NHMe c1 CI NMe, CI NMe, C1 H H 0-CI 0-CI 0-F Et Et Et Et Et Me Et Et H H H H H Me H H Y X Rz K’ TABLE IS.
NO Me Et 107 110, mp 181-184°C Ph i 108 ( I ) KOHlMeOH (2) HCI (3) HOAclNaNO, 109 12. 8) Several syntheses of the imidazo[1,2-althieno[3,2-fl[l,4ldiazepine system have appeared. Reaction of thienodiazepine-2-thione 112 (a key intermediate also used in the preparation of the corresponding tetrazolo and oxadiazolo tricyclic diazepines) with 2,2-diethoxyethylamine led to the diazepine 113, which was in equilibrium with its imino tautomer. Acid-catalyzed cyclization produced the tricyclic imidazole 114 as outlined in Eq.