By Gordon Ethelbert Ward Wolstenholme, Maeve O'Connor
Chapter 1 Chairman's beginning comments (pages 1–3): W. T. J. Morgan
Chapter 2 common Chemistry of the Mucopolysaccharides (pages 4–21): M. Stacey
Chapter three Physicochemical stories on Hyaluronic Acids (pages 22–41): B. S. Blumberg and A. G. Ogston
Chapter four Immunochemical techniques to Polysaccharide and Mucopolysaccharide constitution (pages 42–63): Elvina Kabat
Chapter five Biosynthesis of Mucopolysaccharides: The Uridine Nucleotides of crew a Streptococci (pages 64–84): Albert Dorfman and J. Anthony Cifonelli
Chapter 6 Sulphated Galactosamine?Containing Mucopolysaccharides (pages 85–92): Roger W. Jeanloz, Pierre J. Stoffyn and Monique Tremege
Chapter 7 The Presence in Cartilage of a fancy Containing Chondroitin Sulphate mixed with a Non?Collagenous Protein (pages 93–115): S. M. Partridge and H. F. Davis
Chapter eight The impartial Heteropolysaccharides in Connective Tissue (pages 116–189): Z. Disch, A. Danilczenko and G. Zelmenis
Chapter nine N?Containing Saccharides in Human Milk (pages 140–156): Paul Lgyorgy
Chapter 10 The Pharmacological results of Polysaccharides (pages 157–186): Rolf Meier
Chapter eleven Mucopolysaccharides of Gram?Negative micro organism: more moderen Chemical and organic points (pages 187–199): Otto Westphal, Otto Luderitz, Erwin Eichenberger and Erwin Neter
Chapter 12 Mucopolysaccharides linked to Blood team Specificity (pages 200–215): W. T. J. Morgan
Chapter thirteen Blood crew lively ingredients of Plant starting place (pages 216–233): Georg F. Springer
Chapter 14 Mucopolysaccharides of Epithelial Mucus (pages 234–244): Lars Odin
Chapter 15 Glycoproteins of Plasma (pages 245–266): Richard J. Winzler
Chapter sixteen Colloidal homes of Urinary Mucopolysaccharides (pages 268–286): N. F. Maclaga and A. J. Anderso
Chapter 17 The Prosthetic staff of a few Mucoproteins and its dating to Influenza Virus (pages 287–295): Alfred Gottschalk
Chapter 18 Neuraminic Acid (pages 296–313): E. Klenk
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Extra info for Ciba Foundation Symposium - Chemistry and Biology of Mucopolysaccharides
Our analytical figures agree fairly well with those published by these authors, and all the gargoyle extracts from both biopsied and post-mortem material so far examined appear to be similar to each other, containing about 18, 28 and 21 per cent respectively of hexosamine, uronic acid and hexose. The ratio of glucosamine to galactose (employing an ion exchange column separation) was about 5 : 1 in one extract and about 3 . 5 : 1 in the other. Qualitatively, by two-dimensional separations (chromatography followed by electrophoresis and staining with toluidine blue), several acid polysaccharides appeared to be present in the extracts and a small proportion behaved as chondroitin sulphate.
Dische: Dr. Ogston, have you any ideas on this controversy about the proteins in the vitreous humour? I think your findings on complex formations may be related to the fact that some authors found only y-globulin in the vitreous humour and no a- or p-globulin, and others found u- and P-globulin but no y-globulin. I wonder if in these cases the vitreous humour had not been treated somewhat differently before the electrophoresis was carried out. Might not complex formations between the huge excess of hyaluronic acid in the vitreous and the relatively small amount of protein be responsible for such differences in electrophoretic patterns?
The random-coil model consists of a flexible chain of small scattering units, coiled randomly within a large, approximately spherical domain of solution, the density of scattering units TABLE I Filtration Method of preparation (1945) Mix and Snellman (1957) a (&-l)/c at c b dverage value. 3 - Light scattering Sedimentation, diffusion 550 random coil much elongated spheroid 250- rod somewhat stiff random coil 480 extended swollen sphere d Conclusions of the original authors; see text for comment.